주요경력

주요경력

▶ 학력

2013 – 2018 Ph.D. Biochemistry, Kangwon National University

2011 – 2013 M.S. Disease Diagnostics and Therapeutics, Kangwon National University

2007 – 2011 B.S. Biochemistry, Kangwon National University

▶ 주요경력

▶ 주요연구분야

- 암세포 전이의 분자 기작 연구

- 바이오 의약소재 개발 연구

▶ 주요연구업적

Yeon Woo Jung, Bo Mi Lee, Manh Tuan Ha, Manh Hung Tran, Jeong Ah Kim, Suhyun Lee, Jeong Hyung Lee, Mi Hee Woo, Byung Sun Min. (2019). Lignans from Saururus chinensis exhibit anti-inflammatory activity by influencing the Nrf2/HO-1 activation pathway. Archives of Pharmacal Research

Phuong Thao Tran, Nguyen Tien Dat, Nguyen Hai Dang, Pham Van Cuong, Suhyun Lee, Cheol Hwangbo, Chau Van Minh, Jeong-Hyung Lee. (2018). Ganomycin I from Ganoderma lucidum attenuates RANKL-mediated osteoclastogenesis by inhibiting MAPKs and NFATc1. Phytomedicine. 55:1-8

Minna Shin, Bo-Mi Lee, Okwha Kim, Huynh Nguyen Khanh Tran, Suhyun Lee, Cheol Hwangbo, Byung-Sun Min, and Jeong-Hyung Lee. (2018). Triterpenoids from Ziziphus jujuba induce apoptotic cell death in human cancer cells through mitochondrial reactive oxygen species production. Food & Function. 9(7):3895-3905

Phi-Long Tran, Phuong Thao Tran, Huynh Nguyen Khanh Tran, Suhyun Lee, Okwha Kim, Buyng-Sun Min, Jeong-Hyung Lee. (2018). A prenylated flavonoid, 10-oxomornigrol F, exhibits anti-inflammatory effects by activating the Nrf2/heme oxygenase-1 pathway in macrophage cells. International Immunopharmacology. 55:165-173

Nara Tae, Tran Manh Hung, Okwha Kim, Namho Kim, Suhyun Lee, Sunghun Na, Byung-Sun Min, and Jeong-Hyung Lee. (2017). A cassaine diterpene alkaloid, 3β-acetyl-nor-erythrophlamide, suppresses VEGF-induced angiogenesis and tumor growth via inhibiting eNOS activation. Oncotarget. 8(24): 38886–38901

Manh Tuan Ha, Manh Hung Tran, Thien Thuong Phuong, Jeong Ah Kim, Mi Hee Woo, Jae Sue Choi, Suhyun Lee, Jeong Hyung Lee, Hyeong Kyu Lee, Byung Sun Min. (2017). Cytotoxic and apoptosis-inducing activities against human lung cancer cell lines of cassaine diterpenoids from the bark of Erythrophleum fordii. Bioorg Med Chem Lett. 27(13):2946-2952.

Nara Tae, Suhyun Lee, Okwha Kim, Juhee Park, Sunghun Na and Jeong-Hyung Lee. (2017). Syntenin promotes VEGF-induced VEGFR2 endocytosis and angiogenesis by increasing ephrin-B2 function in endothelial cells. Oncotarget. 8(24):38886-38901.

C Hwangbo, N Tae, S Lee, O Kim, O K Park, J Kim, S-H Kwon and J-H Lee. (2016). Syntenin regulates TGF-β1-induced Smad activation and the epithelial-to-mesenchymal transition by inhibiting caveolin-mediated TGF-β type I receptor internalization. Oncogene. 35:389-401.

Suhyun Lee, Sol-Yip Choi, Young-Yeon Choo, Okwha Kim, Phuong Thao Tran, Cuong To Dao, Byung-Sun Min, Jeong-Hyung Lee. (2015). Sappanone A exhibits anti-inflammatory effects via modulation of Nrf2 and NF-κB. International Immunopharmacology. 28:328–336.

Young-Yeon Choo, Suhyun Lee, Phi-Hung Nguyen, Wanju Lee, Mi-Hee Woo, Byung-Sun Min and Jeong-Hyung Lee. (2015). Caffeoylglycolic acid methyl ester, a major constituent of sorghum, exhibits anti-inflammatory activity via the Nrf2/heme oxygenase-1 pathway. RSC Advances. 5:17786-17796.

Solip Choi, Van Thu Nguyen, Nara Tae, Suhyun Lee, Sungwoo Ryoo, Byung-Sun Min, Jeong-Hyung Lee. (2014). Anti-inflammatory and heme oxygenase-1 inducing activities of lanostane triterpenes isolated from mushroom Ganoderma lucidum in RAW264.7 cells. Toxicology and Applied Pharmacology. 280:434–442.

Kim N, Hwangbo C, Lee S, Lee JH. (2013). Eupatolide Inhibits PDGF-induced Proliferation and Migration of Aortic Smooth Muscle Cells Through ROS-dependent Heme Oxygenase-1 Induction. Phytother Research. 27(11):1700-7.

Lee S, Seo J, Ryoo S, Cuong TD, Min BS, Lee JH. (2012). Malabaricone C inhibits PDGF-induced proliferation and migration of aortic smooth muscle cells through induction of heme oxygenase-1. Journal of Cellular Biochemistry. 113(9):2866-76.