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본문

김옥화(20.03~21.05) 박사후연구원

생화학과

Tel033-250-8519

E-mailkah3173@kangwon.ac.kr

주요경력

주요경력

학력

학사 강원대학교 생화학과 (2009.03 ~ 2012.08)

석사 강원대학교 일반대학원 생화학과 (2012.09 ~ 2014.09)

박사 강원대학교 일반대학원 생화학과 (2014.09 ~ 2020.02)

 

주요연구분야

암세포 유래 엑소좀 내 miRNAs 규명 및 기능연구

천연물 유래 화합물에 의한 염증저해효과 기전 연구

 

주요연구업적

논문(2015~현재)

2015

Molecular Medicine Reports

Chelidonine suppresses migration and invasion of MDA-MB-231 cells by inhibiting formation of the integrin-linked kinase/PINCH/α-parvin complex.

2015

International immunopharmacology

Sappanone A exhibits anti-inflammatory effects via modulation of Nrf2 and NF-κB

2016

Journal of natural medicines

Anti-inflammatory terpenylated coumarins from the leaves of Zanthoxylum schinifolium with α-glucosidase inhibitory activity

2017

Oncotarget

Syntenin promotes VEGF-induced VEGFR2 endocytosis and angiogenesis by increasing ephrin-B2 function in endothelial cells

2017

International immunopharmacology

Sappanone A inhibits RANKL-induced osteoclastogenesis in BMMs and prevents inflammation-mediated bone loss

2017

Oncotarget

A cassaine diterpene alkaloid, 3β-acetyl-nor-erythrophlamide, suppresses VEGF-induced angiogenesis and tumor growth via inhibiting eNOS activation

2018

International immunopharmacology

A prenylated flavonoid, 10-oxomornigrol F, exhibits anti-inflammatory effects by activating the Nrf2/heme oxygenase-1 pathway in macrophage cells

2018

International journal of molecular medicine

Desoxyrhapontigenin inhibits RANKLinduced osteoclast formation and prevents inflammationmediated bone loss

2018

Food & function

Triterpenoids from Ziziphus jujuba induce apoptotic cell death in human cancer cells through mitochondrial reactive oxygen species production

2019

Phytomedicine

Ethanol extract of Polyscias fruticosa leaves suppresses RANKL-mediated osteoclastogenesis in vitro and LPS-induced bone loss in vivo

2019

Food and chemical toxicology

Protective effects of extract of Cleistocalyx operculatus flower buds and its isolated major constituent against LPS-induced endotoxic shock by activating the Nrf2/HO-1 pathway

 

(24341) 강원도 춘천시 강원대학길 1 강원종합기술연구원 TEL : 033-250-8936 FAX : 033-259-5748 E-MAIL : kiit@kangwon.ac.kr

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