본문
주요경력
주요경력
▶ 학력
학사 강원대학교 생화학과 (2009.03 ~ 2012.08)
석사 강원대학교 일반대학원 생화학과 (2012.09 ~ 2014.09)
박사 강원대학교 일반대학원 생화학과 (2014.09 ~ 2020.02)
▶ 주요연구분야
암세포 유래 엑소좀 내 miRNAs 규명 및 기능연구
천연물 유래 화합물에 의한 염증저해효과 기전 연구
▶ 주요연구업적
논문(2015~현재)
2015 | Molecular Medicine Reports | Chelidonine suppresses migration and invasion of MDA-MB-231 cells by inhibiting formation of the integrin-linked kinase/PINCH/α-parvin complex. |
2015 | International immunopharmacology | Sappanone A exhibits anti-inflammatory effects via modulation of Nrf2 and NF-κB |
2016 | Journal of natural medicines | Anti-inflammatory terpenylated coumarins from the leaves of Zanthoxylum schinifolium with α-glucosidase inhibitory activity |
2017 | Oncotarget | Syntenin promotes VEGF-induced VEGFR2 endocytosis and angiogenesis by increasing ephrin-B2 function in endothelial cells |
2017 | International immunopharmacology | Sappanone A inhibits RANKL-induced osteoclastogenesis in BMMs and prevents inflammation-mediated bone loss |
2017 | Oncotarget | A cassaine diterpene alkaloid, 3β-acetyl-nor-erythrophlamide, suppresses VEGF-induced angiogenesis and tumor growth via inhibiting eNOS activation |
2018 | International immunopharmacology | A prenylated flavonoid, 10-oxomornigrol F, exhibits anti-inflammatory effects by activating the Nrf2/heme oxygenase-1 pathway in macrophage cells |
2018 | International journal of molecular medicine | Desoxyrhapontigenin inhibits RANKL‑induced osteoclast formation and prevents inflammation‑mediated bone loss |
2018 | Food & function | Triterpenoids from Ziziphus jujuba induce apoptotic cell death in human cancer cells through mitochondrial reactive oxygen species production |
2019 | Phytomedicine | Ethanol extract of Polyscias fruticosa leaves suppresses RANKL-mediated osteoclastogenesis in vitro and LPS-induced bone loss in vivo |
2019 | Food and chemical toxicology | Protective effects of extract of Cleistocalyx operculatus flower buds and its isolated major constituent against LPS-induced endotoxic shock by activating the Nrf2/HO-1 pathway |